Prophylactic role of curcumin against cyclosporine-induced nephrotoxicity: Histological and immunohistological study
نویسندگان
چکیده
منابع مشابه
Renoprotective Effects of Naringenin and Olive Oil against Cyclosporine- Induced Nephrotoxicity in Rats
Background: Prolonged use of cyclosporine A for prevention of allograft rejection is associated with nephrotoxicity development. Naringenin and olive oil are beneficial dietary antioxidants with potential renoprotective properties. This study aimed to evaluate the therapeutic effect of naringenin and olive oil in alleviating cyclosporine induced nephrotoxicity in rats by the assessment of renal...
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Cadmium (Cd) is a well-known human carcinogen and a potent nephrotoxin. Curcumin, the yellow bioactive component of turmeric has established its antioxidant activities. The aim of this study was to investigate the protective role of curcumin against Cd induced nephrotoxicity. The rats were treated once daily by oral gavage for five days and divided into four groups of 8 rats each: control, Cd a...
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Lithium is an element which has been used as salts of chloride or carbonate for many years in the treatment of some psychological disorders such as mania, bipolar or schizophrenic diseases. Chronic application of lithium may induce some serious nephropathies such as natriuresis, renal tubular acidosis, tubulointerstitial nephritis progression to progressive chronic kidney disease and hypercalce...
متن کاملrenoprotective effects of naringenin and olive oil against cyclosporine- induced nephrotoxicity in rats
background: prolonged use of cyclosporine a for prevention of allograft rejection is associated with nephrotoxicity development. naringenin and olive oil are beneficial dietary antioxidants with potential renoprotective properties. this study aimed to evaluate the therapeutic effect of naringenin and olive oil in alleviating cyclosporine induced nephrotoxicity in rats by the assessment of renal...
متن کاملCyclosporine nephrotoxicity.
After more than 20 years of cyclosporine use its nephrotoxicity remains a significant clinical problem. Cyclosporine-induced renal injury has been described in solid organs recipients and in patients treated for autoimmune diseases. It is manifested in 2 distinct and well characterized forms, acute nephrotoxicity and chronic nephrotoxicity. This communication reviews the current literature anal...
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ژورنال
عنوان ژورنال: General Physiology and Biophysics
سال: 2010
ISSN: 0231-5882
DOI: 10.4149/gpb_2010_01_85